Sexual Health

Tadalafil (Generic Cialis®)

What is Tadalafil?

Tadalafil is a medication used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH) and, in some cases, pulmonary arterial hypertension (PAH). Tadalafil is known commercially under the name Cialis® when used for ED and BPH, and Adcirca® when used for PAH. It belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors.

How Does Tadalafil Work?

Tadalafil works by relaxing the blood vessels in the penis, allowing for greater blood flow during sexual arousal. It works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which breaks down cyclic guanosine monophosphate (cGMP). cGMP is a substance that is produced in response to sexual stimulation and that facilitates smooth muscle relaxation and vasodilation in the penis. By inhibiting PDE5, tadalafil allows cGMP to build up, facilitating an erection.

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Indications for Use

  1. Erectile Dysfunction (ED):
    • Use: Tadalafil is taken as needed, approximately 30 minutes before sexual activity, or once a day at lower doses for daily use.
    • Dosage: Common doses are 10 mg and 20 mg for use as needed, and 2.5 mg and 5 mg for daily use.
  2. Benign Prostatic Hyperplasia (BPH):
    • Use: Tadalafil is taken once a day to relieve symptoms of BPH, such as difficulty urinating, weak flow, and a frequent urge to urinate.
    • Dosage: The recommended dose is 5 mg per day.
  3. Pulmonary Arterial Hypertension (PAH):
    • Use: For the treatment of PAH, tadalafil is taken regularly, usually once a day.
    • Dosage: The recommended dose is 40 mg (two 20 mg tablets) once a day.

Side Effects

Like all medicines, tadalafil can cause side effects. Common side effects include:

  • Headache
  • Indigestion
  • Back pain
  • Muscle pain
  • Facial redness
  • Nasal congestion

Serious Side Effects

  • Erection that is painful or lasts longer than 4 hours (priapism)
  • Sudden loss of vision in one or both eyes (a rare problem called non-arteritic anterior ischaemic optic neuropathy)
  • Sudden hearing loss or ringing in the ears
  • Dizziness or fainting

Contraindications and Precautions

Tadalafil should not be used by people who:

  • Take nitrates for chest pain or heart problems, as the combination can cause a dangerous drop in blood pressure.
  • Are allergic to tadalafil or any of its ingredients
  • Have serious heart problems or have had a recent stroke or heart attack.
  • Have low blood pressure or uncontrolled high blood pressure
  • Have serious liver or kidney problems.

Interactions with Other Medications

Tadalafil may interact with other medications, which may increase the risk of serious side effects:

  • Nitrates: Concurrent use may cause a severe drop in blood pressure.
  • Alpha blockers: It may cause postural hypotension (low blood pressure when standing).
  • Other medications for erectile dysfunction: It should not be combined with other treatments for ED.
  • Protease inhibitors for HIV: They can increase levels of tadalafil in the blood, increasing the risk of side effects.

How to Take Tadalafil

For erectile dysfunction:

  • Use as needed: Take it approximately 30 minutes before sexual activity. Do not take it more than once a day.
  • Daily Use: Take it at the same time every day, regardless of sexual activity.

For benign prostatic hyperplasia:

  • Take it at the same time each day.

For pulmonary arterial hypertension:

  • Follow your doctor's instructions. It is usually taken once a day.

Conclusion

Tadalafil is an effective medication for the treatment of erectile dysfunction, benign prostatic hyperplasia and pulmonary arterial hypertension when used correctly. If you experience erection problems, symptoms of BPH, or have PAH, consult a healthcare professional to determine if tadalafil is right for you. At Dzeus, we offer confidential consultations and personalized treatments to help you manage these conditions and improve your quality of life.