Sildenafil is a medication used primarily to treat erectile dysfunction (ED) in men and, in some cases, pulmonary arterial hypertension (PAH). It is known commercially under the name Viagra®, among others. Sildenafil belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors.
Sildenafil works by relaxing the blood vessels in the penis, allowing for greater blood flow during sexual arousal. It works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which breaks down cyclic guanosine monophosphate (cGMP). cGMP is a substance that is produced in response to sexual stimulation and that facilitates smooth muscle relaxation and vasodilation in the penis. By inhibiting PDE5, sildenafil allows cGMP to build up, facilitating an erection.
Like all medicines, Sildenafil can cause side effects. Common side effects include:
Sildenafil should not be used by people who:
Sildenafil may interact with other medications, which may increase the risk of serious side effects:
For erectile dysfunction:
For pulmonary arterial hypertension:
Sildenafil is an effective medication for the treatment of erectile dysfunction and pulmonary arterial hypertension when used correctly. If you experience erection problems or have PAH, consult a healthcare professional to determine if sildenafil is right for you. At Dzeus, we offer confidential consultations and personalized treatments to help you manage these conditions and improve your quality of life.